Open-target sparse sensing of biological agents using DNA microarray

Sensing of Heavy Metals Using Caenorhabditis elegans DNA Microarray

Previously we reported that the possibility of sensing of chemical substances using gene expression patterns analyzed by DNA microarray using Caenorhabditis elegans (C. elegans) as a sensor (Matsuno et al., 2002, 2006). In this study, we evaluated sensitivity and selectivity of above system using a customized DNA microarray for heavy metal responded genes. The results showed that this system sh...

Gene Identification from Microarray Data for Diagnosis of Acute Myeloid and Lymphoblastic Leukemia Using a Sparse Gene Selection Method

Background: Microarray experiments can simultaneously determine the expression of thousands of genes. Identification of potential genes from microarray data for diagnosis of cancer is important. This study aimed to identify genes for the diagnosis of acute myeloid and lymphoblastic leukemia using a sparse feature selection method. Materials and Methods: In this descriptive study, the expressio...

DNA microarray experiments: biological and technological aspects.

DNA microarray technologies, such as cDNA and oligonucleotide microarrays, promise to revolutionize biological research and further our understanding of biological processes. Due to the complex nature and sheer amount of data produced from microarray experiments, biologists have sought the collaboration of experts in the analytical sciences, including statisticians, among others. However, the b...

Biological Sensing and DNA Templated Electronics Using Conjugated Polymers

dna electrochemical nanobiosensors for the detection of biological agents

in this study, we explained a nanobiosensor for dna sequence detection, featuring sequence specificity, cost efficiency, speed, and ease of use. without the need for labels or indicators, it may be ideal for the detection of biological agents. this review describes recent advances in electrochemical impedance spectroscopy (eis) with an emphasis on using nanoparticles and nanotechnology. a power...